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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-106b
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79
Methods transfection, CCK-8 assay, transwell assay, flow cytometry, RT-PCR, Western blot
Expression pattern up-regulated
Functional description Suppression of miR-106b inhibited Y79 cell proliferation and migration. The upregulation of Runx3 after miR-106b suppression ascertained that Runx3 is a tumor-suppressor in retinoblastoma and is a target of miR-106b.
PubMed ID 28901461
Year 2017
Title miR106b regulates retinoblastoma Y79 cells through Runx3.
Drug-related ncRNA NO

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